Staff Profile
Dr Emily Mavin
Research Project Manager
- Email: [email protected]
- Address: Faculty of Medical Sciences, Newcastle University
MG.269 William Leech Building
Medical School
Framlington Place
Newcastle upon Tyne
NE2 4HH
Background
In my role as a Research Project Manager, I support a number of research projects within the Faculty of Medical Sciences (HUNTER, BIO-FLARE, PSORT/SIGNATURE and A*STAR-Bio). My projects all have a translational aspect to them and include both observational and interventional clinical trials. This requires working between the University, Trust and Funders to ensure adherence to all relevant regulatory guidelines.
I am responsible for the general project management that also includes budget monitoring & forecasting, milestone reporting and coordinating regular study management meetings.
I have a BSc in Molecular Biology and a PhD in Immunology and have worked in Translational research within academia since 2010.
Publications
- Mavin E, Nicholson L, Amed RS, Gao F, Dickinson A, Wang Xiao-nong. Human regulatory T cells mediate transcriptional modulation of dendritic cell function. The Journal of Immunology 2017, 198(1), 138-146.
- Mavin E, Nicholson L, Dickinson A, Wang XN. Regulatory T cells modulate dendritic cell maturation and function at a transcriptional level. In: ICI 2016 International Congress of Immunology. 2016, Melbourne, Australia: Wiley-VCH Verlag.
- Nicholson L, Mavin E, Minto L, Irving J, Dickinson A, Wang XN. Gene Expression Profiling Implicates Attenuation of NFkB Signalling By Regulatory T Cells in Modulating Dendritic Cell Function. In: 57th Annual Meeting and Exposition of the American Society of Hematology (ASH). 2015, Orlando, FL, USA: American Society of Hematology.
- Nicholson L, Mavin E, Minto L, Irving J, Dickinson A, Wang XN. Gene Expression Profiling Implicates Attenuation of NFkB Signalling By Regulatory T Cells in Modulating Dendritic Cell Function. In: 57th ASH Annual Meeting 2015. 2015, Orlando, USA: American Society of Hematology.
- Mavin E, Nicholson L, Ahmed R, Dickinson A, Wang XN. Treg treated dendritic cells are defective in initiating cutaneous GVH reactions. In: 41st Annual Meeting of the European Society for Blood and Marrow Transplantation. 2015, Istanbul, Turkey: Nature Publishing Group.
- Mavin E, Dickinson A, Wang XN. Do Cryopreserved Regulatory T Cells Retain Their Suppressive Potency?. Transplantation 2013, 95(11), e68-e70.
- Mavin E, Atarod S, Collin M, Dickinson A, Wang X. An association between skin homing T-cells and graft-versus-host disease. In: 38th Annual Meeting of the European Group for Blood and Marrow Transplantation (EBMT). 2012, Geneva, Switzerland: Nature Publishing Group.
- O'Boyle G, Fox CR, Walden HR, Willet JD, Mavin ER, Hine DW, Palmer JM, Barker CE, Lamb CA, Ali S, Kirby JA. Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation. Proceedings of the National Academy of Sciences 2012, 109(12), 4598-4603.
- Mavin E, Dickinson AM, Wang XN. Feasibility of using regulatory T cells as an 'off the shelf' cellular reagent. In: European Congress of Immunology. 2012, Glasgow, UK: Wiley-Blackwell.
- Madhra M, Mavin E, Grainger A, Barge D, Wang XN, Walter J, Matthew D, Notarangelo LD, Gennery A. Regulatory T cell subsets, T cell receptor repertoire, and autoantibodies in RAG1-deficient Omenn syndrome. In: 15th Biennial Meeting European Society for Immunodeficiency (ESID). 2012, Florence, Italy: Springer.
- Mavin E, Ahmed SS, O'Boyle G, Turner B, Douglass S, Collin M, Ali S, Dickinson A, Wang X-N. Regulatory T Cells Inhibit CD8+ T-Cell Tissue Invasion in Human Skin Graft-Versus-Host Reactions. Transplantation 2012, 94(5), 456-464.
- Wang X, Turner B, O'Boyle G, Douglass S, Ahmed S, Mavin E, Collin M, Ali S, Dickinson AM. Blocking effector T-cell trafficking contributes to regulatory T-cell mediated suppression of GvHD reactions. In: Bone Marrow Transplantation: 37th European Group for Bone and Marrow Transplantation. 2011, Paris, France: Nature Publishing Group.
- Mavin ER, Dickinson AM, Wang XN. Regulatory T cell suppressive functions are not affected by cryo-preservation. In: Immunology: Annual Congress of the British Society for Immunology. 2011, Liverpool, UK: Wiley-Blackwell Publishing Ltd.
- Mavin E, Verdon B, Carrie S, Saint-Criq V, Powell J, Kuttruff CA, Ward C, Garnett JP, Miwa S. Real-time measurement of cellular bioenergetics in fully differentiated human nasal epithelial 2 cells grown at air-liquid-interface. American Journal of Physiology-Lung Cellular and Molecular Physiology 2020, 318(6), L1158-L1164.
- Gardner AI, Haq IJ, Simpson AJ, Becker KA, Gallagher J, Saint-Criq V, Verdon B, Mavin E, Trigg A, Gray MA, Koulman A, McDonnell MJ, Fisher AJ, Kramer EL, Clancy JP, Ward C, Schuchman EH, Gulbins E, Brodlie M. Recombinant Acid Ceramidase Reduces Inflammation and Infection in Cystic Fibrosis. American Journal of Respiratory and Critical Care Medicine 2020, 202(8), 1133-1145.
- Reis M, Mavin E, Nicholson L, Green K, Dickinson A, Wang X. Mesenchymal stromal cell-derived extracellular vesicles attenuate dendritic cell maturation and function. Frontiers in Immunology 2018, 9, 2538.
- Ghimire S, Weber D, Mavin E, Wang XN, Dickinson AM, Holler E. Pathophysiology of GvHD and other HSCT-related major complications. Frontiers in Immunology 2017, 8, 79.